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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP2 All Species: 23.33
Human Site: S401 Identified Species: 51.33
UniProt: Q99490 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99490 NP_001116244.1 1192 124674 S401 N S Q E W T L S R S I P E L R
Chimpanzee Pan troglodytes XP_509171 1192 124575 S401 N S Q E W T L S R S I P E L R
Rhesus Macaque Macaca mulatta XP_001116285 1192 124611 S401 N S Q E W T L S R S I P E L R
Dog Lupus familis XP_538251 744 80557
Cat Felis silvestris
Mouse Mus musculus Q3UHD9 1186 124492 S395 N S Q E W T L S R S I P E L R
Rat Rattus norvegicus Q8CGU4 1186 124419 S395 N S Q E W T L S R S I P E L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508850 681 74893
Chicken Gallus gallus XP_421880 1213 132309 S421 N S Q E W T L S R S V P E L K
Frog Xenopus laevis Q6NRL1 864 95088 Q98 Y L T G T Y V Q E E S P E G G
Zebra Danio Brachydanio rerio XP_001921526 831 91170 L65 S A L V H R Y L T G T Y V Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 Y229 S F N T V Y N Y Y T K M A H F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 97.8 60.5 N.A. 95.3 95.6 N.A. 28.6 42.4 38.5 38.6 N.A. 26.9 N.A. N.A. N.A.
Protein Similarity: 100 99.2 98.3 61.1 N.A. 96.6 96.8 N.A. 37.6 55.7 50.6 49.5 N.A. 41.7 N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 0 86.6 13.3 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 100 100 N.A. 0 100 20 13.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 55 0 0 0 0 10 10 0 0 64 0 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 10 0 0 0 0 0 10 0 0 0 10 10 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 46 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % K
% Leu: 0 10 10 0 0 0 55 10 0 0 0 0 0 55 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 55 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 % P
% Gln: 0 0 55 0 0 0 0 10 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 10 0 0 55 0 0 0 0 0 46 % R
% Ser: 19 55 0 0 0 0 0 55 0 55 10 0 0 0 0 % S
% Thr: 0 0 10 10 10 55 0 0 10 10 10 0 0 0 0 % T
% Val: 0 0 0 10 10 0 10 0 0 0 10 0 10 0 0 % V
% Trp: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 19 10 10 10 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _